After years of weathering the #AfterDark absurdity of the Pac-12 Conference, USC hoped moving to the Big Ten might help kick most of those bizarre midnight romps from its calendar.

Of course, geographic sense only matters so much in college football when there's millions to be made from broadcast rights. Fox had the third choice this week among the networks and chose the best available game. That's why USC and Michigan State will kick off at 8 p.m. Saturday. Which means, in East Lansing, Mich., the game should wrap somewhere around 2:30-3 a.m.

There were two such kickoffs in the Big Ten last season, and only one that included a team hopping three time zones to the west. USC won that 8 p.m. game against Rutgers in quarterback Jayden Maiava's debut.

The Spartans arrived in L.A. on Thursday to give them plenty of time to acclimate. Jonathan Smith, who previously coached at Oregon State, understands what such a late kickoff requires. Still, you could understand why Michigan State might not be thrilled at the prospect of playing so late.

USC will have its own time-zone trouble to deal with next week, when it kicks off at 9 a.m. PDT in a road matchup with Illinois. This weekend, the bigger question for USC will be if the fans arrive well-rested -- or at all.

"Both teams gotta deal with it," coach Lincoln Riley said. "We gotta handle it well, our crowd needs to handle it well. At the end of the day, it's a game, it's being played, it's being played in the Coliseum, and we expect to win and we expect to have a really good crowd behind us. We're not going to make excuses about it."

Here are four things to watch as USC takes on Michigan State:

Few quarterbacks in college football have started the season at the breakneck pace that Jayden Maiava has managed through three weeks. Maiava is averaging more than 14 yards per attempt -- the most of any quarterback in the nation by three full yards -- while completing 68% of his passes, almost a 10% improvement from last season.

There's no reason to think that trend won't continue against Michigan State.

The Spartans rank 118th in the nation -- and worst in the Big Ten -- in pass defense, and that's after playing teams like Youngstown State and Western Michigan. They haven't seen anything yet like USC's passing offense, and especially receiver Makai Lemon, who ranks behind only Ohio State's Jeremiah Smith in receiving yards (315-311) this season in the Big Ten.

Michigan State has been stingy this season against the run, so it could be tough to find much of a rhythm on the ground. That means a potential big game for Maiava.

Through three games, USC's rejuvenated pass rush actually leads the nation in sacks with 14. Michigan State, meanwhile, has allowed the second-most sacks of any Big Ten team this season.

That formula could mean a long afternoon for Spartan quarterback Aidan Chiles, who Riley said this week poses "the biggest challenge we've faced up to this point" at the position. The Long Beach native appears to be putting it all together as a passer, but it's Chiles' dual threat ability that could be especially dangerous against a front four that's been aggressive early in the season..

He's tied for the conference lead in rush attempts among quarterbacks at 10 per game.

"When you add in Chiles' athleticism, that definitely adds an entirely new element," Riley said. "So it'll be a big focus point for us to be able to keep him in the pocket, to contain him in there."

When under heavy pressure, Chiles has been much less effective. His completion percentage drops from 79% in a clean pocket to 48% in a pressured one.

Both teams could be without their most dynamic pass catcher on Saturday.

USC wideout Ja'Kobi Lane, last year's Big Ten leader in touchdown receptions, is questionable after he sat out practice on Wednesday. Riley wouldn't comment on whether he'd be available for the game.

Similarly, the status of Spartan receiver Nick Marsh was up in the air as of Friday. Marsh made the trip to L.A., in spite of dealing with a lower leg injury. He's by far Michigan State's most dynamic weapon on offense and his absence would be significant, if he's unable to go.

With Lane hobbled, keep a close eye on freshman Tanook Hines, who pulled down a stunning acrobatic catch last Saturday at Purdue.

Riley raved about the freshman earlier this week.

"He goes after the ball with a unique mindset for a freshman," Riley said. "You talk about a guy who really attacks the ball. He's played physical. He's a really good blocker. He's done a good job of picking up our system. ... He's an all-ball guy. There's no fluff to this guy. He's an edgy, tough competitor."

USC vs. Michigan State: Four things to watch for Saturday